James Cormier

Associate Professor
Physical Sciences Centre
(902) 867-5080

B.Sc. 1981 St. Francis Xavier University
Ph.D. 1987 McGill University (Synthesis of Nucleoside and Oligonnucleotide Analogues)

Assistant Professor 1989/91 University of Windsor, Department of Chemistry and Biochemistry
Assistant Professor 1991/95 Trent University, Department of Chemistry

Conference Presentations

The Johns Hopkins University, School of Hygiene and Public Health 1987/89 (P.S. Miller and P.O.P. Ts'o, Oligonucleoside Methylphosphonate Synthesis)


Embryotoxicity of Polychlorinated Diphenyl Ethers to Japanese Medaka (Oryzias latioes)
C.D. Metcalfe, T.L. Metcalfe, J.F. Cormier, S.Y. Heustis, A.J. Niimi
Environ. Toxicology and Chem., 16, 1749-54 (1997)

Normal Phase HPLC Resolution of 5'-Protected Nucleoside Methylphosphonamidites
James F. Cormier and Jeffry B. Plomley
J. Chromatogr., 662, 405-410 (1994)

Selectivity in the Catalytic Transfer Hydrogenolysis of Silyl Ether Protecting Groups
James F. Cormier, Methvin B. Isaac and Li-Feng Chen
Tetrahedron Lett., 34, 243-246 (1993)

An Improvement in the Stereospecific Synthesis of Dinucleoside Methylphosphonates
J. F. Cormier and Tina Pannunzio
Tetrahedron Lett., 32, 7161-7164 (1991)

Removal of TBDMS Protecting Groups from Carbohydrates Using Catalytic Transfer Hydrogenation
J.F. Cormier
Tetrahedron Lett., 32, 187-188 (1991)

The Synthesis and Use of 5'-O-MMT-Uridine-2'-TBDMS-3'-O-N,N-Diisopropylaminomethylphosphine for Preparation of Antisense Oligonucleotide Analogues
J.F. Cormier and S. Roeloffzen
80th CSC Conference, Windsor, Ontario, 1997

The Synthesis of Diribonucleoside Methylphosphonates
J.F. Cormier and S. Roeloffzen
79th CSC Conference, St. John's, Newfoundland, 1996

Synthesis of Homooligonucleoside Methylphposphonates by Solution Phase Polymerisation of Methylphosphonamidites
J.F. Cormier, R.A. Vissers and J.B. Plomley
78th CSC Conference, Guelph, Ontario, 1995

Embryotoxicity of Chlorinated Diphenyl Ethers to the Japanese Medaka
T.P. Marshall, C.D. Metcalfe, J.F. Cormier, C.B. Lumsden and A.J. Niimi
International Association of Great Lakes Research, Windsor, Ontario, 1994

Studies on the Stereospecific Synthesis of Antisense Oligonucleotide Analogues: Mechanism of the Acid Calalysed Phosphonamidite Route
J.F. Cormier and J.B. Plomley
76th CSC Conference, Sherbrooke, Quebec, 1993

Calatylic Transfer Hydrogenolysis of Monomethoxytrityl and t-Butyldimethylsilyl Ethers: Deprotection of Ribonucleosides
J.F. Cormier
73rd CIC Conference, Halifax, Nova Scotia, 1990

Research Interests

Oligonucleotide analogue synthesis, organic synthesis